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DR.ALTHEA PDRN Reju 5000 Cream

DR.ALTHEA PDRN Reju 5000 Cream

Premium Beauty
Regular price £18.97 GBP
Regular price Sale price £18.97 GBP
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Size

Product details

Brand
DR.ALTHEA
Size
20g
Scent
Fragrance-free formula
Skin type
All, esp. sensitive & reactive
Item form
Gel cream
Texture & finish
Gel-cream; absorbs in seconds, smooth natural finish, no tackiness
Product benefits
Calms reactive skin and helps rebuild resilience over time
Active ingredients
PDRN (sodium DNA) 5,000 ppm, centella asiatica leaf water 5%, panthenol, triple hyaluronic acid complex
Special ingredients
Aureobasidium pullulans ferment, tocopherol, beta-sitosterol
When to use
AM & PM, daily
Free from
Fragrance Free, Drying Alcohol Free, Paraben Free
Claims
Vegan, Sensitive Skin Safe, pH Balanced, SCPN Notified, CPNP Notified, Dermatologically tested; DermaTest Germany certified
Made in
Made in Korea

About this item

  • PDRN at 5,000 ppm: a meaningful concentration of the regenerating active that helps reactive skin rebuild resilience and feel less fragile over time.
  • Centella leaf water at 5%: soothes redness on contact and quiets easily upset skin.
  • Hydration at multiple depths: a triple hyaluronic acid complex plus panthenol strengthens the barrier and holds moisture in, without heaviness.
  • Effortless under SPF: absorbs within seconds with no tackiness, shine or white cast, and layers over serums without pilling or shifting.
  • Balanced skin environment: aureobasidium pullulans ferment supports the skin microbiome while vitamin E protects against daily stress.
  • Certified for sensitive skin: dermatologically tested with DermaTest Germany certification; vegan, fragrance-free and paraben-free.
£18.97(£94.85/100g)
In stock
Return within 61 days of receipt — hassle-free refund Returnable within 61 days of receiptItem can be returned in its original condition for a full refund within 61 days of receipt.Read full return policy
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View full details
  • Vegan
  • Fragrance Free
  • Drying Alcohol Free
  • Paraben Free
  • Sensitive Skin Safe
  • pH Balanced
  • Made in Korea
  • SCPN Notified
  • CPNP Notified

Description

The DR.ALTHEA PDRN Reju 5000 Cream gives reactive, easily upset skin a reliable place to settle. It centres on PDRN at 5,000ppm, a regenerating active that helps skin rebuild resilience and feel less fragile over time. Centella Asiatica Leaf Water soothes redness on contact. Panthenol strengthens the barrier and holds moisture in.

A triple hyaluronic acid complex adds hydration at multiple depths, leaving skin soft without any heaviness. Aureobasidium Pullulans Ferment supports a balanced skin environment. The gel-cream texture absorbs quickly and sits neatly under SPF or makeup. There is no tackiness and no greasy finish.

The formula is vegan, fragrance-free, and paraben-free. It has been dermatologically tested and carries the DermaTest Germany certification. Safe for daily use on sensitive skin, morning and evening, all year round.

What This Moisturiser Does for Your Skin

The DR.ALTHEA PDRN Reju 5000 Cream is built to help sensitive skin feel settled and stronger. Reactive skin often sits in a cycle of irritation and fragility. This cream works to interrupt that cycle with focused, well-researched ingredients.

PDRN, listed as Sodium DNA in the formula, sits at 5,000ppm. It is a regenerating active that helps skin rebuild its natural resilience. With regular use, skin becomes less reactive and better able to cope with daily stressors. The concentration here is meaningful. Many formulas include PDRN as a token addition. At 5,000ppm, it has enough presence to make a real difference.

The formula is fragrance-free, paraben-free, and vegan throughout. It has been dermatologically tested and certified by DermaTest Germany. That certification gives real confidence to people managing compromised or easily triggered skin. The vegan formulation also means no animal-derived ingredients anywhere in the product.

The Texture and How It Feels

Despite its name, the DR.ALTHEA PDRN Reju 5000 Cream behaves like a gel-cream hybrid. It spreads easily across the skin with a light, fluid slip. It absorbs within seconds and leaves no trace of greasiness or heaviness.

The finish is smooth and natural. There is no tackiness, no shine, and no white cast. You can apply SPF directly over the top without any slipping or pilling. That makes it a practical daily choice, not just a treatment-day option.

Vinyl Dimethicone and Caprylyl Methicone give the formula its silky slip. These conditioners create a weightless barrier that feels protective without blocking pores. For dry or reactive areas, you can apply a slightly thicker layer. It absorbs fully either way, leaving skin calm and soft to the touch.

The formula also layers well over other products. It sits after essences and serums without disturbing them. If you follow with an oil or sleeping pack, the cream stays in place beneath. There is no balling up or product shifting.

The Ingredients That Nourish Your Skin

Centella Asiatica Leaf Water makes up 5% of the formula. It soothes redness and quiets irritated skin from the first application. Panthenol, a form of vitamin B5, strengthens the skin barrier and reduces moisture loss. Together they form a reliable calming foundation for reactive skin.

Hydration comes from a triple hyaluronic acid complex. Sodium Hyaluronate softens skin texture at the surface. Hyaluronic Acid plumps and smooths. Hydrolysed Hyaluronic Acid reaches deeper layers to give skin a fuller, more comfortable feel. The three forms work at different depths so moisture reaches the skin at more than one level.

Aureobasidium Pullulans Ferment is a probiotic-derived ferment that supports a balanced skin environment. This is particularly helpful when sensitivity links to microbiome disruption. Tocopherol, a form of vitamin E, protects skin from environmental stress. Beta-Sitosterol is a plant-derived sterol that adds soothing support and fortifies the skin lipid layer.

The formula contains no added fragrance, no parabens, and no unnecessary additives. Every ingredient serves a clear purpose. For sensitive skin, that kind of restraint matters as much as what is included. A shorter, cleaner list means fewer opportunities for irritation.

Day, Night, or Both

The DR.ALTHEA PDRN Reju 5000 Cream suits morning and evening use. In the morning, apply it after your serum or essence. Follow with SPF as your final step. The lightweight finish sits comfortably under sunscreen and makeup without any pilling.

In the evening, the cream works without interruption. Apply a standard amount on calm nights. When skin feels more reactive, apply a thicker layer over affected areas. Leave it to absorb and work through the night.

It also works as a semi-final step in your evening routine. If your skin needs a richer seal overnight, layer a sleeping pack over the top. A drop of facial oil works well too. The water-based formula sits beneath oil-based products without disruption.

On drier or colder days, you can apply a second pass over particularly tight areas. It absorbs fully, so there is no uncomfortable build-up. Skin feels more comfortable and settled after each layer.

Who This Moisturiser Is For

This cream suits all skin types, but it was built with sensitive and reactive skin at its core. If your skin flushes with certain products or flares in cold weather, this cream offers grounded, consistent support. It is a good fit for year-round use.

Those rebuilding a compromised barrier will find PDRN and beta-sitosterol support active recovery, not just surface comfort. Oily and combination skin types will value the lightweight finish. Dry skin benefits from the triple hyaluronic acid complex and panthenol retaining moisture throughout the day.

The DR.ALTHEA PDRN Reju 5000 Cream is sensitive skin tested and dermatologically certified. It is built from a restrained, honest ingredient list with no fragrance and no parabens. If you want a cream you can rely on every morning and evening, this is a straightforward choice.


Disclaimer: Packaging and product images may be updated by the manufacturer without notice. The item you receive may differ in appearance from the images shown, and colours may vary slightly between screens.

How to Use

How to use: After cleansing and toning, take a pea-sized amount and smooth it evenly over your face and neck. Use gentle pressing motions to help the formula absorb fully. For areas that feel particularly reactive or dry, apply a slightly thicker layer.

Frequency: Morning and evening. The lightweight texture makes it comfortable for twice-daily use throughout the year.

Routine placement: Apply as your final moisturising step. Use after any water-based serums or essences. If adding a facial oil or sleeping pack, apply this cream first. Layer the other product over the top afterwards. In the morning, follow with SPF as your last step.

As a targeted treatment: Apply a generous layer over patches of redness, dryness, or irritation. Leave on overnight or until fully absorbed. This works particularly well after skin has been disrupted by a new product or environmental stressors.

Storage: Keep in a cool, dry place away from direct sunlight. Refrigerating before use can enhance the soothing feel on reactive skin, though this is optional.

Size and longevity: Available in 20g. With twice-daily use on the full face, this size typically lasts four to six weeks.

Pairs well with: A low-pH cleanser, a hydrating toner or essence, a targeted serum, and an SPF in the morning.

Ingredients

Ingredients List

Aqua, Glycerin, Centella Asiatica Leaf Water, Panthenol, Butylene Glycol, Dicaprylyl Ether, 1,2-Hexanediol, Vinyl Dimethicone, Caprylyl Methicone, Hydrogenated Polydecene, Pentylene Glycol, Dicaprylyl Carbonate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium DNA, Dimethiconol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetearyl Olivate, Aminomethyl Propanediol, Sorbitan Olivate, Glyceryl Acrylate/Acrylic Acid Copolymer, Xanthan Gum, Ethylhexylglycerin, Sodium Hyaluronate, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Phytate, Tocopherol, Aureobasidium Pullulans Ferment, Caprylic/Capric Triglyceride, Beta-Sitosterol, Hydrogenated Lecithin, Polyglyceryl-4 Caprate, Polyglyceryl-6 Caprylate, SH-Oligopeptide-1

Key Ingredients

PDRN (Sodium DNA) 5,000ppm - supports skin regeneration and resilience; Centella Asiatica Leaf Water 5% - soothes and calms irritated, reddened skin; Panthenol - moisturises and soothes, strengthens the skin barrier; Triple Hyaluronic Acid Complex (Sodium Hyaluronate, Hyaluronic Acid, Hydrolyzed Hyaluronic acid) - hydrates at multiple skin depths to plump and smooth; Aureobasidium Pullulans Ferment - probiotic-derived ferment that supports skin microbiome balance; Tocopherol (Vitamin E) - antioxidant that protects skin from environmental stress; Beta-Sitosterol - plant-derived sterol with soothing and barrier-supporting properties

Disclaimer: Ingredients may be updated by the manufacturer without notice. For the most current and accurate list, always refer to the product packaging.

Complete Your Calm Ritual

Better together

Complete Ritual

£39.91 £37.92

BUILD YOUR CALM RITUAL

Routine Recommendation

Step 1
DR.ALTHEA Pore Refresh Grinding Cleansing Balm

Cleanser

DR.ALTHEA Pore Refresh Grinding Cleansing Balm

£12.47

Step 2
DR.ALTHEA Rapid Mild Acid Rescue Pore Pad

Toner

DR.ALTHEA Rapid Mild Acid Rescue Pore Pad

£16.97

Step 3
DR.ALTHEA 0.1% Gentle Retinol Serum

Serum

DR.ALTHEA 0.1% Gentle Retinol Serum

£16.97

Step 4
DR.ALTHEA PDRN Reju 5000 Cream

Cream

DR.ALTHEA PDRN Reju 5000 Cream

£18.97

Step 5
DR.ALTHEA Aqua Glowing Sunscreen

Sunscreen

DR.ALTHEA Aqua Glowing Sunscreen

£14.97


PDRN 5,000 ppm · 5% panthenol · 20 g

Concentrated comfort for skin that feels stretched thin.

PDRN Reju 5000 is Dr.Althea’s ointment-inspired calming cream — vegan, probiotic-derived PDRN at 5,000 ppm with generous panthenol and centella, in a texture that feels far lighter than it works.

Sensitive-feeling skinOintment-type, light finishVegan formula
DR.ALTHEA Cream 20g DR.ALTHEA PDRN Reju 5000 Cream

What does it do?

For the days your skin needs settling.

A small tube that earns its place in the moments skin feels least agreeable.

Visibly settled

Five percent centella leaf water and 5% panthenol help calm the look and feel of temporary redness and tightness.

Supple and bouncy

PDRN at a meaningful 5,000 ppm supports the look of smoother, bouncier, more resilient-feeling skin over time.

Hydration in layers

A triple hyaluronic-acid complex hydrates at more than one depth, so comfort lasts beyond the first hour.

What's in it?

Generous where it counts.

Every headline number here is printed on the tube.

5000

Biome PDRN (sodium DNA)

A vegan, probiotic-derived PDRN at 5,000 ppm — the ingredient this cream is named for, chosen for supple, smooth-looking skin.

5%

Panthenol

Pro-vitamin B5 at 50,000 ppm helps hold moisture in and keeps the skin barrier feeling steady.

5%

Centella leaf water

Centella asiatica leaf water at 50,000 ppm brings its familiar calming character to every application.

DR.ALTHEA PDRN Reju 5000 Cream - experience

How does it feel?

Rich, but it doesn’t sit heavy.

A cream that feels rich without being heavy — reviewers describe it as lightweight to use and easily absorbed, with skin left feeling softer and smoother.

TextureRich cream
FeelAbsorbs well, not heavy
FinishSoft, smooth

Choose your Dr.Althea cream

Which cream fits your skin today?

Intensive comfort, everyday calm or richer moisture — pick your pace.

Compare DR.ALTHEA PDRN Reju 5000 Cream DR.ALTHEA PDRN Reju 5000 CreamYou’re viewing DR.ALTHEA 345 Relief Cream DR.ALTHEA 345 Relief CreamView product DR.ALTHEA 147 Barrier Cream DR.ALTHEA 147 Barrier CreamView product DR.REJU-ALL Advanced LC-Ceramide Barrier Cream DR.REJU-ALL Advanced LC-Ceramide Barrier CreamView product CENTELLIAN24 Expert Madeca Cream Active Renew PDRN CENTELLIAN24 Expert Madeca Cream Active Renew PDRNView product CENTELLIAN24 Madeca Cream Time Reverse CENTELLIAN24 Madeca Cream Time ReverseView product
Best forReactive-feeling skin that wants concentrated comfortSensitive-feeling, blemish-prone skin that wants everyday calmNormal to dry skin that often feels tight or shows dry patchesBarrier repair, lasting moisture, calmed rednessFirms, restores the skin barrier and evens skin toneCalms irritation, smooths fine lines and strengthens the skin barrier
Formula focusPDRN 5,000 ppm with 5% panthenol and 5% centella leaf waterTea tree leaf water, niacinamide and ceramide NPPeony flower extract, ceramide NP and seven hyaluronic-acid formsLong-chain ceramide 1% (patented), Niacinamide, PanthenolTECA-PDRN complex 20, 000 ppm, 8-form hyaluronic acid complexActive-TECA centella complex (12 extracts), niacinamide, retinol
ExperienceOintment-inspired yet lightweight, with a soft finishLightweight, non-sticky cream that layers easilyRich yet silky cream with a non-greasy finishLightweight, fast-absorbingElastic-hold creamMedium-weight cream
Routine roleTargeted calming step or generous overnight layerEveryday calming moisturiser for all skin typesFinal moisturising step, morning and nightAM under SPF or as the final evening stepAM & PMAM or PM

Is it for you?

Made for skin having a demanding week.

If any of these sound familiar, keep this tube close.

  • Sensitive- or reactive-feeling skin that wants focused comfort
  • Skin that looks temporarily red or feels tight in patches
  • Anyone who likes a generous overnight layer on difficult days
  • Those who want an ointment-style cream without the heavy feel
Bought on a whim, assuming I'd be duped

Purchased this on a whim after seeing it appear on many social accounts. Assumed I would be duped to be honest, but truthfully it is a lovely cream to use. Very lightweight and my skin feels much softer after two weeks of use.

Keep a little concentrated calm within reach.

DR.ALTHEA PDRN Reju 5000 Cream £18.97